Ion Chromatography (IC)
Ion Chromatography (IC) is a type of high performance liquid chromatography (HPLC), which is a liquid chromatography method for analyzing anions and cations.
Ion chromatography can help you identify and quantify organic and inorganic ions, ranging from the traditional pharmaceutical industry to the cosmetics industry. T,C&A Lab's analysis services based on ion chromatography provide you with a state-of-the-art IC platform to meet your needs for the analysis of anions, cations, and organic compounds.
Detection principle
Most ionized substances will ionize and produce conductance in solution. Through the detection of conductance, the ionization degree of most ionized substances can be analyzed. Since most ionized substances are completely ionized in dilute solution, the content of the tested substance can be detected by measuring the conductivity value. Therefore, the universal detector of ion chromatography is mainly based on conductance detector.
Detection capabilities
- Anion analysis
- Cation analysis
- Organic compounds
The first and preferred method (the most basic application).
Simultaneous determination of alkali metals, alkaline earth metals, organic amines and ammonium elements, analysis of transition metals, rare earth elements and valence states.
Water-soluble and polar compounds, organic acids, organic amines, sugars, amino acids, antibiotics.
Strengths
- Fast and convenient
- High sensitivity
- Good selectivity
- Simultaneous analysis of multiple ionic compounds
- The separation column has good stability and high capacity
The average analysis time of 7 common anions (F-, Cl-, Br-, NO2-, NO3-, SO42-, PO43-) and 6 common cations (Li+, Na+, NH4+, K+, Mg2+, Ca2+) is less than that of 8min, respectively. It takes only 3min to reach the baseline separation of the above seven most important common anions with a high efficiency and rapid separation column.
The concentration range of ion chromatography analysis is as low as μg/L (1-10 μg/L) to hundreds of mg/L.
The selectivity of the IC method for the analysis of inorganic and organic anions and cations can be achieved by selecting appropriate separation methods, separation columns and monitoring methods. Compared with HPLC, the relative selectivity of immobilization in IC has a greater impact.
Compared with photometric method and atomic absorption method, the main advantage of IC is that it can detect multiple components in the sample at the same time. It only takes a short time to get all the information of anions, cations and sample composition.
Different from the silica gel packing used in HPLC, the high pH stability of the IC column packing allows the use of strong acids or strong bases as eluents, which is beneficial to expand the application range.
In conclusion, T,C&A Lab can offer IC services that can solve materials testing related problem. Finally, please complete the form to have an expert discuss your needs.
Reference
- Liu, Jing-Min, et al. Advanced analytical methods and sample preparation for ion chromatography techniques. RSC advances 5.72 (2015): 58713-58726.
Note: this service is for Research Use Only and Not intended for clinical use.
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Techniques
- Atomic Absorption Spectroscopy (AAS)
- Atomic Force Microscope
- Auger Electron Spectroscopy
- Electron Backscatter Diffraction
- Energy Dispersive Spectrometer (EDS)
- Focused Ion Beam (FIB)
- Fourier Transform Infrared Spectroscopy (FTIR)
- Gas Chromatography - Mass Spectrometry (GC-MS)
- Gel Permeation Chromatography (GPC)
- Glow Discharge-Mass Spectrometry (GD-MS)
- IGA Gas Adsorption System
- Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)
- Ion Chromatography (IC)
- Laser Ablation-Inductively Coupled Plasma Mass Spectrometer (LA-ICP-MS) System
- Nuclear Magnetic Resonance (NMR)
- Raman Spectrometer
- Rutherford Backscattering Spectrometry (RBS)
- Scanning Electron Microscope (SEM)
- Secondary Ion Mass Spectroscopy (SIMS)
- Thin-Layer Chromatography (TLC)
- Time of Flight Secondary Ion Mass Spectrometry (TOF-SIMS)
- Total Reflection X-ray Fluorescence
- XPS/ESCA
- X-Ray Diffraction (XRD)
- X-Ray Fluorescence (XRF)
- X-ray Reflectivity (XRR)